Publications

Complete list of Stavros Taraviras publications available at Google Scholar and NCBI PubMed search

Selected publications:

• Landskron L., Bak J., Adamopoulos A., Kaplani K., Moraiti M., Lisa G van den Hengel, Ji-Ying Song, Onno B Bleijerveld, Joppe Nieuwenhuis, Tatjana Heidebrecht, Linda Henneman, Marie-Jo Moutin, Marin Barisic, Taraviras S., Anastassis Perrakis, Thijn R Brummelkamp Posttranslational modification of microtubules by the MATCAP detyrosinase. Science. April 2022
• Karantzelis N, Petropoulos M, De Marco V, Egan DA, Fish A, Christodoulou E, Will DW, Lewis JD, Perrakis A, Lygerou Z and Taraviras S Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells,  Frontiers in Pharmacology, April 2022 13:860682. 

• Antonopoulos I., Daoussis D., Lalioti ME, Markatseli TE, Drosos AA, Taraviras S., Andonopoulos AP.,  Liossis SN C. B cell depletion treatment decreases CD4+IL4+ and CD4+CD40L+ T cells in patients with systemic sclerosis. Rheumatol Int 39, 1889–1898 (2019).

• Mougkogianni M, Kalogeropoulou A., Giakoumakis N, Lygerou Z, Taraviras S., Ιn vivo imaging of DNA-bound minichromosome maintenance complex in embryonic mouse cortex, STAR Protocols, Volume 2, Issue 1, 2021, 100234 

• Champeris Tsaniras S, Delinasios GJ, Petropoulos M, Panagopoulos A, Anagnostopoulos AK, Villiou M, Vlachakis D, Bravou V, Stathopoulos GT, Taraviras S. DNA Replication Inhibitor Geminin and Retinoic Acid Signaling Participate in Complex Interactions Associated With Pluripotency. Cancer Genomics Proteomics. 2019 Nov-Dec;16(6):593-601.     

• Ioannidis K., Angelopoulos I., Gakis G., Karantzelis N., Spyroulias GA, Lygerou Z., Taraviras S. 3D Reconstitution of the Neural Stem Cell Niche: Connecting the Dots. Frontiers in bioengineering and biotechnology. October 2021, 9:705470.

• Ioannidis K., Danalatos RI, Champeris Tsaniras S., Kaplani K., Lokka G., Kanellou A., Papachristou DJ, Bokias G., Lygerou Z, Taraviras S. A Custom Ultra-Low-Cost 3D Bioprinter Supports Cell Growth and Differentiation. Frontiers in bioengineering and biotechnology. November 2020

• Petropoulos M., Champeris Tsaniras S , Taraviras S, & Lygerou Z. Replication licensing aberrations, replication stress, and genomic instability. Trends in biochemical sciences. 2019 September

• Lalioti ME, Kaplani K, Lokka G, Georgomanolis T, Kyrousi C, Dong W, Dunbar A, Parlapani E, Damianidou E, Spassky N, Kahle K, Papantonis A, Lygerou Z, Taraviras S. GemC1 is a critical switch for neural stem cell generation in the postnatal brain. Glia, 2019 July, 67(12), 2360-2373.

• Lalioti ME, Arbi M, Loukas I, Kaplani K, Kalogeropoulou A, Lokka G, Kyrousi C, Mizi A, Georgomanolis T, Josipovic N, Gkikas D, Benes V, Politis P, Papantonis A, Lygerou Z, Taraviras S. GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73. Journal of cell science, 2019 June, 132(11)

• Ortiz-Alvarez G, Daclin M, Shihavuddin A, Lansade P, Fortoul A, Faucourt M, Clavreu S, Lalioti ME, Taraviras S, Hippenmeyer S, Livet J, Meunier A,Genovesio A, Spassky N. Adult neural stem cells and multiciliated ependymal cells share a common lineage regulated by the geminin family members. Neuron, 2019 April, 102(1), 159-172

• Kalogeropoulou A, Lygerou Z, & Taraviras S. Cortical development and brain malformations: Insights from the differential regulation of early events of DNA replication. Frontiers in cell and developmental biology, 2019 March, 7, 29.

• Champeris Tsaniras S, Villiou M, Giannou A D, Nikou S, Petropoulos M, Pateras I S, Tserou P, Karousi F, Lalioti ME, Gorgoulis V G, Patmanidi A L, Stathopoulos G T, Bravou V, Lygerou Z, Taraviras S. Geminin ablation in vivo enhances tumorigenesis through increased genomic instability. The Journal of pathology, 2018 June, 246(2), 134-140.

• Arbi M, Pefani D E, Taraviras S, Lygerou Z. Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis. Chromosoma, 2018 June, 127(2), 151-174.

• Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou G, Kardamakis D, Blackwell T S, Taraviras S, Spella M, Stathopoulos G T. Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion. Nature communications, 2018 February, 9(1), 672.

• Kaplani K, Koutsi S, Armenis V, Skondra FG, Karantzelis N, Champeris Tsaniras S, et al. Wound healing related agents: Ongoing research and perspectives. Adv Drug Deliv Rev. 2018 Mar 1

• Kyrousi C, Lygerou Z, Taraviras S. How a radial glial cell decides to become a multiciliated ependymal cell. Glia. 2017 Jul;65(7):1032–42

• Taouki MI, Tasiudi E, Lalioti M-E, Kyrousi C, Skavatsou E, Kaplani K, et al. Geminin participates in differentiation decisions of adult neural stem cells transplanted in the hemiparkinsonian mouse brain. Stem Cells Dev. 2017 Aug 15;26:1214–22.

• Kyrousi C, Lalioti M-E, Skavatsou E, Lygerou Z, Taraviras S. Mcidas and GemC1/Lynkeas specify embryonic radial glial cells. Neurogenesis Austin Tex. 2016;3(1):e1172747.

• Patmanidi AL, Kanellakis NI, Karamitros D, Papadimitriou C, Lygerou Z, Taraviras S. Whole transcriptome data analysis of mouse embryonic hematopoietic stem and progenitor cells that lack Geminin expression. Data Brief. 2016 Jun 1;7:889–93.

• Kyrousi C, Arbi M, Pilz G-A, Pefani D-E, Lalioti M-E, Ninkovic J, et al. Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Dev Camb Engl. 2015 Nov 1;142(21):3661–74

• Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Götz M, Lygerou Z, Taraviras S. 2015. Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development. 142(21):3661-74.
• Karamitros D, Patmanidi AL, Kotantaki P, Potocnik AJ, Bähr-Ivacevic T, Benes V, Lygerou Z, Kioussis D, Taraviras S. 2015 Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 142(1):70-81.
• Champeris Tsaniras S, Kanellakis N, Symeonidou IE, Nikolopoulou P, Lygerou Z, Taraviras S. 2014 Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world? Semin Cell Dev Biol. 30:174-80.
• Symeonidou IE, Kotsantis P, Roukos V, Rapsomaniki MA, Grecco HE, Bastiaens P, Taraviras S, Lygerou Z. 2013 Multi-step loading of human minichromosome maintenance proteins in live human cells. J Biol Chem. 288(50):35852-67.
• Stathopoulou A, Roukos V, Petropoulou C, Kotsantis P, Karantzelis N, Nishitani H, Lygerou Z, Taraviras S. 2012 Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs. PLoS One. 7(3):e34621. doi: 10.1371/journal.pone.0034621.

• Spella M, Kyrousi C, Kritikou E, Guillemot F, Pachnis V, Kioussis D, Lygerou Z, Taraviras S. Geminin regulates self renewal and differentiation decisions in cortical progenitor cells during embryogenesis. (2011). Stem Cells. 29(8):1269-82. 

• Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. 2010. Life without Geminin. Cell Cycle. Aug 15;9(16):3181-5

• Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. 2010. Differential Geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 184(5):2432-2441.

• De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. 2009 The quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing. Proc. Natl. Acad. Sci. U.S.A. 106(47):19807-12.

• Petropoulou C, Kotantaki P, Karamitros D, Taraviras S. 2008 Cdt1 and Geminin in cancer: Markers or triggers of malignant transformation? Frontiers in Bioscience 13: 4485-4494.

• Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. 2007 Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res. 67(22):10899-909.

• Spella M, Britz O, Kotantaki P, Lygerou Z, Nishitani H, Ramsay RG, Flordellis C, Guillemot F, Mantamadiotis T, Taraviras S. 2007. Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle. Neuroscience.

• V. Roukos, M. S. Iliou, H. Nishitani, M. Gentzel, M. Wilm, S. Taraviras, Z. Lygerou 2007. Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma. J Biol Chem. 282:13, 9346-9357.

• G. Xouri, A. Squire, M. Dimaki,B. Geverts, P. J. Verveer,S. Taraviras,H. Nishitani, A. B. Houtsmuller, P. I. H. Bastiaens,  Z.  Lygerou 2007. Dynamic chromatin association of Cdt1 throughout G1 leads to Geminin recruitment onto chromatin. EMBO J. 26, 1303–1314.

• Karakaidos P , Taraviras S. , Vassiliou LV , Zacharatos P, Kastrinakis NG, Kougiou D, Kouloukoussa M, Nishitani H, Papavassiliou AG, Lygerou Z, Gorgoulis VG. 2004. Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1. Am J Pathol. Oct;165(4):1351-65.

• Xouri Z., Lygerou Z. , Nishitani H., Pachnis V., Nurse P., Taraviras S. 2004. The licensing factor cdt1 and its inhibitor Geminin are both down-regulated upon cell cycle exit and over-expressed in cancer cells. Eur J Biochem, The FEBS Journal. Aug;271(16):3368-78.

• Taraviras, S. and Pachnis, V. (1999). Development of the mammalian enteric nervous system. Current Opinion in Genetics and Development. 9, 321-327.

• Taraviras, S., Marcos-Gutierrez, C., Durbec, P., Jani, H., Grigoriou, M., Sukumaran, M., Wang, L., Hynes, M., Raisman, G. and Pachnis V. (1999). Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. Development. 126, 2785-2797.