Stem Cell Laboratory

Publications

NCBI PubMed search for all Stavros Taraviras Papers

Selected publications :

  • Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Götz M, Lygerou Z, Taraviras S. 2015. Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development. 142(21):3661-74.
  • Karamitros D, Patmanidi AL, Kotantaki P, Potocnik AJ, Bähr-Ivacevic T, Benes V, Lygerou Z, Kioussis D, Taraviras S. 2015 Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 142(1):70-81.
  • Champeris Tsaniras S, Kanellakis N, Symeonidou IE, Nikolopoulou P, Lygerou Z, Taraviras S. 2014 Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world? Semin Cell Dev Biol. 30:174-80.
  • Symeonidou IE, Kotsantis P, Roukos V, Rapsomaniki MA, Grecco HE, Bastiaens P, Taraviras S, Lygerou Z. 2013 Multi-step loading of human minichromosome maintenance proteins in live human cells. J Biol Chem. 288(50):35852-67.
  • Stathopoulou A, Roukos V, Petropoulou C, Kotsantis P, Karantzelis N, Nishitani H, Lygerou Z, Taraviras S. 2012 Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs. PLoS One. 7(3):e34621. doi: 10.1371/journal.pone.0034621.
  • Spella M, Kyrousi C, Kritikou E, Guillemot F, Pachnis V, Kioussis D, Lygerou Z, Taraviras S. Geminin regulates self renewal and differentiation decisions in cortical progenitor cells during embryogenesis. (2011). Stem Cells. 29(8):1269-82. 
  • Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. 2010. Life without Geminin. Cell Cycle. Aug 15;9(16):3181-5
  • Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. 2010. Differential Geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 184(5):2432-2441.
  • De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. 2009 The quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing. Proc. Natl. Acad. Sci. U.S.A. 106(47):19807-12.
  • Petropoulou C, Kotantaki P, Karamitros D, Taraviras S. 2008 Cdt1 and Geminin in cancer: Markers or triggers of malignant transformation? Frontiers in Bioscience 13: 4485-4494.
  • Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. 2007 Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res. 67(22):10899-909.
  • Spella M, Britz O, Kotantaki P, Lygerou Z, Nishitani H, Ramsay RG, Flordellis C, Guillemot F, Mantamadiotis T, Taraviras S. 2007. Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle. Neuroscience.
  • V. Roukos, M. S. Iliou, H. Nishitani, M. Gentzel, M. Wilm, S. Taraviras, Z. Lygerou 2007. Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma. J Biol Chem. 282:13, 9346-9357.
  • G. Xouri, A. Squire, M. Dimaki,B. Geverts, P. J. Verveer,S. Taraviras,H. Nishitani, A. B. Houtsmuller, P. I. H. Bastiaens,  Z.  Lygerou 2007. Dynamic chromatin association of Cdt1 throughout G1 leads to Geminin recruitment onto chromatin. EMBO J. 26, 1303–1314.
  • Karakaidos P , Taraviras S. , Vassiliou LV , Zacharatos P, Kastrinakis NG, Kougiou D, Kouloukoussa M, Nishitani H, Papavassiliou AG, Lygerou Z, Gorgoulis VG. 2004. Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1. Am J Pathol. Oct;165(4):1351-65.
  • Xouri Z., Lygerou Z. , Nishitani H., Pachnis V., Nurse P., Taraviras S. 2004. The licensing factor cdt1 and its inhibitor Geminin are both down-regulated upon cell cycle exit and over-expressed in cancer cells. Eur J Biochem, The FEBS Journal. Aug;271(16):3368-78.
  • Taraviras, S. and Pachnis, V. (1999). Development of the mammalian enteric nervous system. Current Opinion in Genetics and Development. 9, 321-327.
  • Taraviras, S., Marcos-Gutierrez, C., Durbec, P., Jani, H., Grigoriou, M., Sukumaran, M., Wang, L., Hynes, M., Raisman, G. and Pachnis V. (1999). Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. Development. 126, 2785-2797.